Editorial Type:
Article Category: Research Article
 | 
Online Publication Date: 21 May 2025

Comparison of clinical outcomes between percutaneous transhepatic biliary drainage with local lithotripsy and ERCP alone for treating intrahepatic bile duct stones

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DOI: 10.9738/INTSURG-D-25-00030
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Abstract

Objectives:

To compare the efficacy of percutaneous transhepatic biliary drainage (PTCD) combined with local litholytic therapy versus endoscopic retrograde cholangiopancreatography (ERCP) alone for treating intrahepatic bile duct stones.

Methods:

A retrospective study of 160 patients divided into joint group (JG, n=80; PTCD with litholytic therapy) and ERCP group (EG, n=80). Parameters compared included surgical metrics, short-term efficacy indicators, liver function tests, inflammatory markers, complications, and recurrence rates.

Results:

The JG showed significantly shorter operative times, less blood loss, shorter hospital stays, lower costs, and faster recovery than the EG (all P<.05). At 3 months postoperatively, liver function indicators (TBIL, ALT, AST, ALP) and inflammatory markers (CRP, PCT) were significantly improved in the JG compared to the EG. Perioperative complication rates (7.5% vs. 18.75%) and 12-month recurrence rates (7.5% vs. 18.8%) were lower in the JG (P=.035).

Conclusions:

Combined PTCD with local litholytic therapy offers advantages over ERCP alone, including reduced trauma, faster recovery, improved liver function, and lower complication and recurrence rates.

Contributor Notes

Correspondence: 259176299@qq.com

The authors declare no potential conflicts of interest.

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